Ethos Precision Medicine Umbrella Study for Hemangiosarcoma (Ethos-PUSH)
Currently EnrollingDescription
Hemangiosarcoma (HSA) is an aggressive cancer in dogs and carries a poor prognosis. There are limited therapeutic options for the treatment of HSA, with none currently providing a significant opportunity for long-term survival. Ethos Discovery’s previous work in HSA has taught us that HSA is not a single cancer, but is rather at least four different subtypes of cancer, each characterized by a different genomic mutation. Previous studies evaluating drugs for the treatment of HSA have shown variable results and the discovery of these different subtypes could explain this phenomenon.
Ethos Discovery now seeks to deliver a highly advanced clinical trial program investigating the use of novel drugs for the treatment of HSA with the goal of curing this aggressive cancer. This study will ask if drugs specifically matched to the genomic subtypes of patients with HSA will result in improved outcomes.
Eligibility criteria
- Any dog that is diagnosed with a ruptured splenic tumor and is pursuing surgery for splenectomy.
- No evidence of metastasis as determined via chest x-rays, and during surgery.
- Dogs weighing more than 5kg and less than 45kg
Pet Owner Resources
Click the links below for more information about eligibility, steps, timelines and treatments associated with this study.
- Study Guide: Hemoabdomen – ETHOS-PUSH Phase 1
- Study Guide: Hemangiosarcoma – ETHOS-PUSH Phase 2
Interested?
Enroll or request more information below