Our Studies/ Scientific Programs

Summary of Study: The Stratification of Outcomes for Lymphoma In Dogs with Relapsed Lymphoma (SOLID-Relapse) study is a clinical trial focused on the follow- up of dogs previously enrolled in Ethos-SOLID. This population of relapsed patients will add the perspective of longitudinal analysis and provide a unique opportunity to study the role of functional precision medicine in treatment of relapsed lymphoma. 

Advancing bone cancer research in dogs through Osteosarcoma Summary of Study Osteosarcoma is the most prevalent form of bone cancer in dogs, sharing many biological similarities with the disease in humans. Unfortunately, even when a tumor is completely removed through surgery, over 90% of dogs eventually die because the cancer spreads to their lungs. The

Clinical Study: Diet and probiotic therapy for chronic enteropathy in dogs Currently Enrolling Comparison of diet and probiotic vs. diet alone to control clinical signs of chronic enteropathy and diarrhea in dogs Study Goals: This study aims to evaluate a new probiotic-based therapeutic for chronic enteropathy and chronic diarrhea in dogs. Targeted alteration of the

Minimally Invasive treatment options for bone cancer in dogs This clinical trial is evaluating a new, minimally invasive treatment for dogs with osteosarcoma, a common and aggressive bone cancer. This innovative approach, called Cryoablation and Cementoplasty for local Control of Osteosarcoma Management (CAPCOM), offers a limb-sparing alternative for dogs who may not be good candidates

Study on vessel sealing devices in elective spay/neuter operations for exotic pets Summary of Study: Spay and neuter procedures are surgeries recommended for and performed on most exotics companion mammals for population control, to prevent reproductive diseases including cancer, and to help reduce behavioral concerns. Evaluation of surgical techniques is of great importance to these

Minimally-invasive surgical bone cancer treatment for dogs CURRENTLY ENROLLING The MIMIC clinical trial is open for enrollment. Ethos Discovery is investigating a new minimally-invasive surgical treatment for canine osteosarcoma that has metastasized, or spread, to the lungs. This study is subsidized and all procedures will be provided at an affordable, low cost. Eligibility Criteria: •

TIDBITS: Bio-markers for Immune-Mediated Thrombocytopenia and response to immunosuppression in dogs Goal: Investigate whether exosome RNA profiles in ITP differ in treatment of naive dogs compared to those that respond with immunosuppression Inclusion Criteria: Canine patients with platelet count < 40K Clinical evidence of bleeding Weight ≥ 2kg Ability to administer vincristine No other causes

We are studying a novel live probiotic product typically found in the gut of healthy dogs to evaluate the ability of this probiotic to resolve diarrhea in dogs.

We are collecting blood samples from eligible French Bulldogs to research biomarkers associated with hemorrhages (bleeding) in French bulldogs.

Ethos Discovery seeks to investigate a new approach to reducing hemorrhages (bleeding) in French Bulldogs following slipped discs in their back.

Is your dog undergoing surgery for a ruptured splenic tumor? Ethos Discovery would love to have you and your dog participate in our clinical trial! We are evaluating drugs for the treatment of HSA with the goal of curing this aggressive cancer.

Despite years of active research in the field, high mortality rates associated with sepsis have remained unchanged over the last three decades; we aim to change this!