Study of Local Administration of Hemostatic Gel in Canine Epistaxis (SOLACE)
OpenSummary of Study:
The trial aims to evaluate the tolerability and adverse event profile of hemostatic gel in the setting of canine epistaxis of any cause. With this, we also are studying the potential hemostatic activity of hemostatic gel in canine epistaxis. Canine epistaxis was found to be a result from a variety of causes, including trauma, foreign bodies, infections, coagulopathies, and neoplasia.
Initially, 18 dogs with epistaxis of any cause will be enrolled to assess the tolerability of hemostatic gel. If 0/18 dogs tolerate hemostatic gel applications, the study will stop. If hemostatic gel is tolerated in ≥1 of the initial 18 dogs, a second cohort of 18 dogs will be recruited.
The trial aims to evaluate the tolerability and adverse event profile of hemostatic gel in the setting of canine epistaxis of any cause. With this, we also are studying the potential hemostatic activity of hemostatic gel in canine epistaxis. Canine epistaxis was found to be a result from a variety of causes, including trauma, foreign bodies, infections, coagulopathies, and neoplasia.
This is a prospective, observational, multicenter, pilot study.
Inclusion Criteria
We will consider any dog with active epistaxis, unilateral or bilateral, of any underlying cause, including those secondary to underlying pathology or secondary to nasal turbinate biopsy.
Interested?
Enroll or request more information below.