Our Studies/ Scientific Programs

Summary of Study Osteosarcoma is the most prevalent form of bone cancer in dogs, sharing many biological similarities with the disease in humans. Unfortunately, even when a tumor is completely removed through surgery, over 90% of dogs eventually die because the cancer spreads to their lungs. The BONES study seeks to create a “biobank” by

Goal: Investigate whether exosome RNA profiles in ITP differ in treatment of naive dogs compared to those that respond with immunosuppression Inclusion Criteria: Canine patients with platelet count < 40K Clinical evidence of bleeding Weight ≥ 2kg Ability to administer vincristine No other causes of thrombocytopenia found on routine screening Can be included with a

Goal: Investigate whether biomarker RNA profiles can predict response to AR blockers for proteinuria in dogs with PLN. Inclusion Criteria: Dogs with chronic proteinuria (UPC >0.5) for which pre- and post-renal causes have been excluded (UPC >0.5 confirmed on at least two separate occurrences >2 weeks apart) Dogs should have been started on a low

This clinical trial is evaluating a new, minimally invasive treatment for dogs with osteosarcoma, a common and aggressive bone cancer. This innovative approach, called Cryoablation and Cementoplasty for local Control of Osteosarcoma Management (CAPCOM), offers a limb-sparing alternative for dogs who may not be good candidates for amputation due to other health issues. The CAPCOM

Canine Lymphoma Clinical Trial Study Goals: The Stratification of Outcomes for Lymphoma In Dogs (SOLID) study is a clinical trial focused on better understanding the genetics behind canine lymphoma. By studying changes in the DNA of these cancers, researchers hope to identify patterns that could lead to more personalized treatment options. The goal is to find markers

FICUSS Study Study Goals: FICUSS Study looks to improve understanding of Feline Idiopathic Cystitis. The collected samples will be used to help better understand the underlying pathophysiology of this disease, which can then be used to aid in the development of novel diagnostic tests and targeted therapies for this condition. Eligibility criteria: Male cats greater

Currently Enrolling Comparison of diet alone vs. diet and probiotic to control clinical signs of chronic enteropathy in dogs Study Goals: This study aims to address the unmet of chronic enteropathy and, in particular, chronic diarrhea in dogs. Treatments for this condition are often empirical and nonspecific. Recently, altering the gut microbiota in patients with

CURRENTLY ENROLLING The MIMIC clinical trial is open for enrollment. Ethos Discovery is investigating a new minimally-invasive surgical treatment for canine osteosarcoma that has metastasized, or spread, to the lungs. This study is subsidized and all procedures will be provided at an affordable, low cost. Eligibility Criteria: • Dogs weighing >5 kgs with a diagnosis

We are collecting blood samples from eligible French Bulldogs to research biomarkers associated with hemorrhages (bleeding) in French bulldogs.

Ethos Discovery seeks to investigate a new approach to reducing hemorrhages (bleeding) in French Bulldogs following slipped discs in their back.

Current chemotherapy treatments involve a direct injection into the tumor. We would like to use surgically removed lung tissue to better understand how drugs behave when they are injected into lung tumors in dogs, as well as humans, with lung tumors.

Postoperative regurgitation is a common side effect of general anesthesia; it is of clinical concern due to the increased risk of pneumonia. This study seeks to define the rate at which intravenously administered MNTX in healthy dogs is metabolized. Once defined, a future study will evaluate the efficacy of this treatment in reducing postoperative regurgitation in dogs.